Ending Hyperoxaluria. Together.
Whether you’re living with hyperoxaluria or standing beside someone who is, you’re part of a powerful community.
Together, we bring hope to families through care, education, and breakthrough research—moving closer every day to a cure.

Understanding Hyperoxaluria
Hyper
(too much)
oxal
(oxalate)
uria
(in the urine)
Hyperoxaluria can be caused by a genetic disorder, eating too many oxalate-rich foods or an intestinal disease. In some people the cause of the disease is not known but may result from changes in the way kidneys handle normal amounts of oxalate. Early diagnosis and treatment are important to the long-term health of your kidneys.
Living with Hyperoxaluria
Life with hyperoxaluria may come with unique challenges, but you don’t have to navigate them alone. Whether you’re newly diagnosed or have been managing the condition for years, OHF is here to support you every step of the way—with resources, connections, and guidance to help you live fully and confidently.
Ready to begin? Start with Hyperoxaluria, explore Daily Management, and learn how Getting Involved can make a difference.
Our Impact




Please visit our OHF Grants Funded page to explore the impact of these initiatives and this research.
Our Impact




Relentless in Our Pursuit of a Cure
We’re working toward the day when hyperoxaluria can be not only effectively treated but ultimately cured.
As the world’s largest private funder of hyperoxaluria research, we don’t just hope for breakthroughs—we make them happen. Our targeted research strategy accelerates treatment development because we know that right now, families around the world are counting on us.
Get Involved
Every Voice Strengthens Our Purpose.
There’s a role for everyone in this mission.
Upcoming Events
Stay Connected, Stay Informed
There’s strength in coming together. Whether we’re sharing research breakthroughs, celebrating milestones, learning through patient meetings and webinars, or finding new ways to advocate—our events build meaningful connections and keep you engaged with what matters most.
About Us
Small Foundation. Bold Mission. Life-Changing Impact.
At OHF, we’re here for one reason: to support every person affected by hyperoxaluria—with hope, expert care, and a community that never gives up.
Because a cure isn’t just possible—it’s inevitable.
The Future We’re Building Together
The Future We’re Building Together
Imagine a world where hyperoxaluria has a cure. Where treatment is effective and accessible. Where families receive diagnoses with knowledge—and with hope.
That world isn’t a dream. It’s our destination.
Join us. The journey ends when we end hyperoxaluria.